Journal article

Acute High-Intensity Interval Exercise Modulates Corticospinal Excitability in Older Adults

JL Neva, B Greeley, B Chau, JK Ferris, CB Jones, R Denyer, KS Hayward, KL Campbell, LA Boyd

Medicine and Science in Sports and Exercise | LIPPINCOTT WILLIAMS & WILKINS | Published : 2022

Abstract

Introduction Acute exercise can modulate the excitability of the nonexercised upper limb representation in the primary motor cortex (M1). Measures of M1 excitability using transcranial magnetic stimulation (TMS) are modulated after various forms of acute exercise in young adults, including high-intensity interval training (HIIT). However, the impact of HIIT on M1 excitability in older adults is currently unknown. Therefore, the purpose of the current study was to investigate the effects of lower limb cycling HIIT on bilateral upper limb M1 excitability in older adults. Methods We assessed the impact of acute lower limb HIIT or rest on bilateral corticospinal excitability, intracortical inhib..

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University of Melbourne Researchers

Grants

Awarded by Canadian Institutes of Health Research


Funding Acknowledgements

This work was funded by a Canadian Institutes of Health Research Project Grant (PJT-148535; principal investigator: L. A. B.). J. L. N. received funding support from the Michael Smith Foundation for Health Research, and J. L. N. and J. K. F. received funding from the Canadian Institutes of Health Research. R. D. received funding support from the Canadian Partnership in Stroke Recovery. K. S. H. received funding support from the Michael Smith Foundation for Health Research (15980) and the National Health and Medical Research Council of Australia (No. 1088449). The authors confirm that the results of this study are presented clearly, honestly, and without fabrication, falsification, or inappropriate data manipulation, and the results of the present study do not constitute endorsement by the American College of Sports Medicine.